Study Of Single And Ten Day Repeat Atopical Applications Of GW842470X Cream On The Skin Of Patients With Atopic Dermatitis

Phase 1 Completed 45 enrolled GlaxoSmithKline

RandomizedParallel-groupTreatment

Summary

The purpose of this study of this study is to investigate the safety, tolerability and pharmacokinetics of GW842470X in patients with atopic dermatitis. GW842470X is an inhibitor of phosphodiesterase 4 (PDE4).

Timeline

Start: 2005-06-10
Primary completion: 2005-12-21
Completion: 2005-12-21

Publications

Ishikawa N, Hattori N, Kohno N, Kobayashi A, Hayamizu T, Johnson M. Airway inflammation in Japanese COPD patients compared with smoking and nonsmoking controls. Int J Chron Obstruct Pulmon Dis. 2015 Jan 23;10:185-92. doi: 10.2147/COPD.S74557. eCollection 2015.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	AWD-12-281	Small molecule	100 mg	Topical
Subject	AWD-12-281	Small molecule	150 mg	Topical
Subject	AWD-12-281	Small molecule	300 mg	Topical
Subject	AWD-12-281	Small molecule	400 mg	Topical
Subject	AWD-12-281	Small molecule	500 mg	Topical
Subject	AWD-12-281	Small molecule	1000 mg	Topical

Study Of Single And Ten Day Repeat Atopical Applications Of GW842470X Cream On The Skin Of Patients With Atopic Dermatitis

Summary

Timeline

Publications

Drugs

Indications