Efficacy and Safety of Dianicline Versus Placebo as an Aid to Smoking Cessation

Phase 3 Completed 602 enrolled Sanofi

RandomizedParallel-groupDouble-blindTreatment

Summary

The primary objective is to demonstrate the efficacy of dianicline as an aid to smoking cessation in cigarette smokers. The main secondary objectives are: to assess the craving for cigarettes, nicotine withdrawal symptoms and the safety of dianicline.

Timeline

Start: 2006-06
Primary completion: 2007-06
Completion: 2007-06

Publications

Livingstone-Banks J, Fanshawe TR, Thomas KH, Theodoulou A, Hajizadeh A, Hartman L, Lindson N. Nicotine receptor partial agonists for smoking cessation. Cochrane Database Syst Rev. 2023 May 5;5(5):CD006103. doi: 10.1002/14651858.CD006103.pub8.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	dianicline	Small molecule	40 mg	—

Indications

No indication recorded.