drugset / Trial / NCT00364871

Efficacy and Safety Study of Combination Therapy to Treat Uncomplicated Obesity

NCT00364871

Phase 2 Completed 410 enrolled Orexigen Therapeutics, Inc
RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to determine the efficacy and safety of 3 combinations of naltrexone and bupropion SR compared to naltrexone alone, bupropion SR alone or placebo.

Timeline

Start
2005-04
Primary completion
2007-03
Completion
2007-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Bupropion Small molecule 400 mg
Subject Naltrexone Small molecule 16 mg
Subject Naltrexone Small molecule 32 mg
Subject Naltrexone Small molecule 48 mg

Indications