drugset

drugset / Trial / NCT00367653

Azithromycin Plus Chloroquine Versus Mefloquine In the Treatment of Uncomplicated P. Falciparum Malaria.

NCT00367653 ↗

Phase 3 Completed 397 enrolled Pfizer

RandomizedParallel-groupOpen-labelTreatment

Summary

To compare Azithromycin plus Chloroquine versus Mefloquine to treat uncomplicated plasmodium falciparum malaria.

Timeline

Start: 2006-11
Primary completion: 2007-09
Completion: 2007-09

Publications

Sagara I, Oduro AR, Mulenga M, Dieng Y, Ogutu B, Tiono AB, Mugyenyi P, Sie A, Wasunna M, Kain KC, Djimde AA, Sarkar S, Chandra R, Robbins J, Dunne MW. Efficacy and safety of a combination of azithromycin and chloroquine for the treatment of uncomplicated Plasmodium falciparum malaria in two multi-country randomised clinical trials in African adults. Malar J. 2014 Nov 25;13:458. doi: 10.1186/1475-2875-13-458.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Azithromycin	Small molecule	1000 mg	Oral
Subject	Chloroquine	Small molecule	600 mg	Oral
Subject	Mefloquine	Unknown	1250 mg	Oral

Indications