drugset / Trial / NCT00368329
Phase I Dose Escalation of Stereotactic Radiosurgical Boost for Locally Advanced Esophageal Cancer
Non-randomizedSingle-groupOpen-labelTreatment
Summary
To study the safety and feasibility of stereotactic radiation dose escalation following neoadjuvant chemotherapy with concurrent conventionally fractionated radiation, by evaluating the acute and late toxicity of treatment.
Timeline
- Start
- 2006-06
- Primary completion
- 2009-03
- Completion
- 2009-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Capecitabine | Small molecule | 825 mg/m2 | Oral |
| Subject | Carboplatin | Small molecule | 2 unknown | Intravenous |
| Subject | Fluorodeoxyglucose | Diagnostic / imaging agent | 5 mbq | Intravenous |
| Subject | Fluorodeoxyglucose | Diagnostic / imaging agent | 10 mbq | Intravenous |
| Subject | fluorouracil | Small molecule | 200 mg/m2 | Intravenous |