drugset / Trial / NCT00374634
Individual Versus Standard Follicle Stimulating Hormone Dose for Controlled Ovarian Stimulation and Insemination
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to test if recombinant follicle stimulating hormone (rFSH) given in individual doses, according to a nomogram we have constructed based on our results from a previous study, results in more patients maturing 2-3 follicles compared to standard dose.
Timeline
- Start
- 2006-09
- Primary completion
- 2008-09
- Completion
- 2008-10
Publications
- Background la Cour Freiesleben N, Lossl K, Bogstad J, Bredkjaer HE, Toft B, Rosendahl M, Loft A, Bangsboll S, Pinborg A, Nyboe Andersen A. Individual versus standard dose of rFSH in a mild stimulation protocol for intrauterine insemination: a randomized study. Hum Reprod. 2009 Oct;24(10):2523-30. doi: 10.1093/humrep/dep239. Epub 2009 Jul 14.
- Freiesleben Nl, Rosendahl M, Johannsen TH, Lossl K, Loft A, Bangsboll S, Friis-Hansen L, Pinborg A, Andersen AN. Prospective investigation of serum anti-Mullerian hormone concentration in ovulatory intrauterine insemination patients: a preliminary study. Reprod Biomed Online. 2010 May;20(5):582-7. doi: 10.1016/j.rbmo.2010.02.007. Epub 2010 Feb 12.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | Recombinant human follicle stimulating hormone (r-hFSH) | Protein / enzyme biologic | 50 iu | — |
| Comparator | Recombinant human follicle stimulating hormone (r-hFSH) | Protein / enzyme biologic | 75 iu | — |
| Comparator | Recombinant human follicle stimulating hormone (r-hFSH) | Protein / enzyme biologic | 100 iu | — |