drugset / Trial / NCT00377247

Active Immunization of Patients With Carcinoma of Oral Cavity or Oropharynx With Autologous Dendritic Cells Transfected With DNA From Autologous Tumor

NCT00377247 ↗

Phase 1 Terminated 5 enrolled University of Pittsburgh
NaSingle-groupOpen-labelTreatment

Summary

The primary goal of this study is to determine if the vaccine can be safely given to subjects, and to see what side effects occur (both good and bad) when they are given this experimental tumor vaccine. During this study, investigators intend to watch for tumor response while examining the effects of this vaccine on the body's immune system after it is given.

Timeline

Start
2009-04
Primary completion
2009-04
Completion
2009-04

Outcome

Outcome not reported

Stopped (Enrollment): “study closed to accrual due to slow accrual”

Drugs

EvaluationDrugModalityDoseRoute
Subject autologous monocyte-derived dendritic cells (DC) transfected with DNA Cell therapy 1e+07 cells Other