drugset / Trial / NCT00378573

Multicenter Evaluation of Docetaxel, Gemcitabine, and Bevacizumab Combination Followed by Bevacizumab Alone in Subjects With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

NCT00378573 ↗

Phase 2 Terminated 17 enrolled Sanofi
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a Phase II prospective, multicenter study evaluating Progression Free Survival (PFS) after first line treatment with the combination of gemcitabine, docetaxel, and bevacizumab in subjects with advanced or metastatic Non-Small Cell Lung Cancer (NSCLC). PFS will be measured from the date of registration (ie, assignment of subject number when subject meets all entry criteria) to the earliest date of documented evidence of progressive disease, or the date of death due to any cause, whichever occurs first.

Timeline

Start
2007-01
Primary completion
2008-09
Completion
2008-09

Outcome

Outcome not reported

Stopped: “Incidence of GI Perforation”

Drugs

EvaluationDrugModalityDoseRoute
Subject Bevacizumab Monoclonal antibody — —
Subject Docetaxel Small molecule — —
Subject Gemcitabine Small molecule — —