drugset / Trial / NCT00378677

Dry Powder Inhalation of Cyclosporine A in Lung Transplant Patients With Bronchiolitis Obliterans Syndrome

NCT00378677

Phase 0 Unknown 7 enrolled University Medical Center Groningen
Non-randomizedSingle-groupOpen-labelTreatment

Summary

The purpose of this study is to investigate whether dry powder inhalation of Cyclosporine A is beneficial in lung transplant patients with Bronchiolitis Obliterans Syndrome. For patients suffering from this syndrome often no therapeutic options are available. Furthermore, the side effects of the maintenance therapy leaves no room for dose increments. The hypothesis for this trial is that when Cyclosporine A is administered locally (in the lungs) chronic rejection can be treated more effectively without extra systemic side effects.

Timeline

Start
2007-02
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Cyclosporine Peptide Inhaled