drugset / Trial / NCT00385008

TREXIMA and RELPAX Gastric Scintigraphy Inside and Outside a Migraine

NCT00385008

Phase 3 Completed 20 enrolled GlaxoSmithKline
RandomizedParallel-groupOpen-labelTreatment

Summary

An evaluation of tablet disintegration and absorption and gastric transit of sumatriptan and naproxen sodium from a TREXIMA tablet and eletriptan from a RELPAX 40mg tablet.

Timeline

Start
2006-09-13
Primary completion
2006-11-24
Completion
2006-11-24

Publications

  • Background Kori S, Byrd S, Doll W, Page R, and Sandefer E. Gastric Emptying and Absorption of a Sumatriptan with RT Technology 85mg and Naproxen Sodium 500mg Tablet. Cephalalgia 2007; Vol 27; 649.
  • Background Kori S, Byrd S, Doll W, Page R, and Sandefer E. Gastroscintigraphic Evaluation of Gastric Emptying and Absorption of Another Conventionally Formulated Triptan. Cephalalgia 2007; Vol 27; 730.
  • Background Kori S, Byrd SC, Doll WJ, Page RC, and Sandefer EP. Gastric Transit and Absorption of Sumatriptan and Naproxen from a Fixed Single-Tablet Sumatriptan RT Technology 85mg and Naproxen Sodium 500mg in Migraineurs both During and Outside a Migraine Attack: Evaluation by Gastric Scintigraphy. Headache 2007; 47(5):751.
  • Background Kori S, Doll WJ, Page RC, Byrd SC, Sandefer EP. Gastric Transit and Absorption of Eletriptan, another Conventionally Formulated Triptan, in Migraineurs both During and Outside a Migraine Attack: Evaluation by Gastric Scintigraphy. Headache 2007; 47(5):752.

Drugs

EvaluationDrugModalityDoseRoute
Subject Eletriptan Small molecule 40 mg
Subject Naproxen Small molecule
Subject Sumatriptan Unknown

Indications