drugset / Trial / NCT00385450

Cardiopulmonary Bypass-Induced Lymphocytopenia and the Potential Effects of Protease Inhibitor

NCT00385450

Phase 1 Terminated 41 enrolled Mayo Clinic
RandomizedSingle-groupDouble-blindPrevention

Summary

In previous studies, 90% of patients who underwent elective cardiopulmonary bypass procedure manifested CD4 counts of less than 500 cells/microliter in the immediate (day 1) post-operative period. This study will investigate whether or not Nelfinavir increases those CD4 counts in the post-operative period.

Timeline

Start
2006-10
Primary completion
2008-10
Completion
2008-10

Drugs

EvaluationDrugModalityDoseRoute
Subject Nelfinavir Other / unclassified 1250 mg

Indications

No indication recorded.