drugset / Trial / NCT00386659

Immune Reconstitution in naïve HIV Patients With CD4 <100 Cells/mL When Treated With Lopinavir or Efavirenz.

NCT00386659

Phase 4 Terminated 60 enrolled Hospital Clinic of Barcelona
RandomizedParallel-groupOpen-labelTreatment

Summary

Pilot, randomized, parallel, open-label, controlled, clinical study evaluating virological response in plasma and extra-plasmatic compartments, together with the degree and kinetics of immune reconstitution in treatment-naïve patients with CD4 count below 100 cells/mL, when treated with tenofovir and abacavir together with lopinavir or efavirenz.

Timeline

Start
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Efavirenz Other / unclassified
Subject lopinavir/ritonavir Unknown
Background Abacavir Other / unclassified
Background Tenofovir Small molecule