drugset / Trial / NCT00387283

Pharmacokinetic Study in Cerebral Spinal Fluid After a Single Dose of AVI-4020

NCT00387283 ↗

Phase 1 Completed 14 enrolled Sarepta Therapeutics, Inc.
Non-randomizedSingle-groupOpen-labelTreatment

Summary

During a clinical study of people with severe West Nile virus infections, it was determined that the drug AVI-4020 crossed the blood-brain barrier. This study will assess the amount of drug that goes across the blood-brain barrier and the drug levels measured in both the blood and urine. The objective of this study is to find out how much and how fast this drug crosses this barrier.

Timeline

Start
2006-10
Primary completion
2006-12
Completion
2009-06

Drugs

EvaluationDrugModalityDoseRoute
Subject AVI-4020 Oligonucleotide (other) — Intravenous

Indications