drugset / Trial / NCT00390338

Vaccine Therapy in Treating Patients With Stage III or Stage IV Melanoma

NCT00390338 ↗

RandomizedParallel-groupOpen-labelTreatment

Summary

RATIONALE: Vaccines made from a person's dendritic cells mixed with tumor peptides and proteins may help the body build an effective immune response to kill tumor cells. Infusing the vaccine directly into the lymphatic system may cause a stronger immune response and kill more tumor cells. PURPOSE: This randomized phase I trial is studying the side effects and best dose of two dendritic cell vaccines in treating patients with stage III or stage IV melanoma.

Timeline

Start
2006-10
Primary completion
2012-05
Completion
2015-01

Drugs

EvaluationDrugModalityDoseRoute
Subject non-polarized dendritic cells Cell therapy — Other
Subject polarized dendritic cells Cell therapy — Other

Indications