drugset

drugset / Trial / NCT00393211

Effect of Etoricoxib to Treat Chronic Low Back Pain (0663-042)

NCT00393211 ↗

Phase 3 Completed 319 enrolled Organon and Co

RandomizedParallel-groupDouble-blindTreatment

Summary

Study the effect of etoricoxib 60 mg and 90 mg compared to placebo to treat chronic low back pain.

Timeline

Start: 2000-04
Primary completion: 2000-11
Completion: 2000-11

Publications

Background Birbara CA, Puopolo AD, Munoz DR, Sheldon EA, Mangione A, Bohidar NR, Geba GP; Etoricoxib Protocol 042 Study Group. Treatment of chronic low back pain with etoricoxib, a new cyclo-oxygenase-2 selective inhibitor: improvement in pain and disability--a randomized, placebo-controlled, 3-month trial. J Pain. 2003 Aug;4(6):307-15. doi: 10.1016/s1526-5900(03)00633-3.
Background Curtis SP, Ng J, Yu Q, Shingo S, Bergman G, McCormick CL, Reicin AS. Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trials. Clin Ther. 2004 Jan;26(1):70-83. doi: 10.1016/s0149-2918(04)90007-0.
Background Sheldon EA, Bird SR, Smugar SS, Tershakovec AM. Correlation of measures of pain, function, and overall response: results pooled from two identical studies of etoricoxib in chronic low back pain. Spine (Phila Pa 1976). 2008 Mar 1;33(5):533-8. doi: 10.1097/BRS.0b013e3181657d24.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Etoricoxib	Small molecule	60 mg	—
Subject	Etoricoxib	Small molecule	90 mg	—

Indications

No indication recorded.