drugset

drugset / Trial / NCT00395044

Gabapentin Treatment of Cannabis Dependence

NCT00395044 ↗

Phase 2 Completed 50 enrolled The Scripps Research Institute National Institute on Drug Abuse (NIDA) · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

This is a study to evaluate the efficacy of the medication gabapentin in treating persons with cannabis dependence.

Timeline

Start: 2006-08
Primary completion: 2008-07
Completion: 2008-07

Outcome

Met primary endpoint

registry analysis (superiority or other test); Gabapentin vs Placebo; p = .029; Mixed Models Analysis NCT00395044 ↗

Publications

Results Mason BJ, Crean R, Goodell V, Light JM, Quello S, Shadan F, Buffkins K, Kyle M, Adusumalli M, Begovic A, Rao S. A proof-of-concept randomized controlled study of gabapentin: effects on cannabis use, withdrawal and executive function deficits in cannabis-dependent adults. Neuropsychopharmacology. 2012 Jun;37(7):1689-98. doi: 10.1038/npp.2012.14. Epub 2012 Feb 29.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Gabapentin	Unknown	1200 mg	—

Indications