drugset / Trial / NCT00395070
A Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 Melanoma
RandomizedParallel-groupSingle-blindTreatment
Summary
To compare the safety and efficacy of Allovectin-7® versus Dacarbazine (DTIC)or Temozolomide (TMZ) in subjects with recurrent stage 3 or stage 4 melanoma.
Timeline
- Start
- 2006-10
- Primary completion
- 2012-03
- Completion
- 2013-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Allovectin-7® | Other / unclassified | 2 mg | Other |
| Comparator | Dacarbazine | Small molecule | 1000 mg/m2 | Intravenous |
| Comparator | Temozolomide | Small molecule | 150 mg/m2 | Oral |
| Comparator | Temozolomide | Small molecule | 200 mg/m2 | Oral |