drugset / Trial / NCT00403286
A Dose-Finding Study Evaluating Safety and Efficacy in Patients With Chronic Obstructive Pulmonary Disease
RandomizedParallel-groupDouble-blindTreatment
Summary
The purpose of the study is to determine the appropriate dose of fluticasone propionate/formoterol fumarate that is closest to Advair Diskus (fluticasone propionate/salmeterol xinafoate using pulmonary function, safety, and levels of study drug in blood plasma in patients with chronic obstructive pulmonary disease.
Timeline
- Start
- 2006-11
- Primary completion
- 2007-05
- Completion
- 2007-05
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Fluticasone propionate | Other / unclassified | 250 ug | Inhaled |
| Subject | Fluticasone propionate | Other / unclassified | 500 ug | Inhaled |
| Subject | Fluticasone propionate | Other / unclassified | 1000 ug | Inhaled |
| Subject | Formoterol | Other / unclassified | 10 ug | Inhaled |
| Subject | Formoterol | Other / unclassified | 20 ug | Inhaled |
| Comparator | salmeterol xinafoate | Unknown | 50 ug | Inhaled |