drugset / Trial / NCT00404378

Study Of Healthy Subjects To Assess The Effect Of Ketoconazole And The Way The Body Will React To Casopitant [GW679769]

NCT00404378

Phase 1 Completed 15 enrolled GlaxoSmithKline
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a two period study of healthy adult subjects to characterize the effect of the dosing of ketoconazole on the the way the body reacts to a dose of GW679769, and to assess the safety profile of oral casopitant with and without ketoconazole. This study will consist of a screening period, two treatment periods and a post-treatment follow-up visit.

Timeline

Start
2006-10-20
Primary completion
2007-01-05
Completion
2007-01-05

Drugs

EvaluationDrugModalityDoseRoute
Subject Casopitant Small molecule 50 mg Oral
Subject Casopitant Small molecule 100 mg Oral
Subject Ketoconazole Small molecule 400 mg