drugset / Trial / NCT00404495
Combination of Irinotecan and Temozolomide in Children With Brain Tumors.
NaSingle-groupOpen-labelTreatment
Summary
This study will assess the rate of objective confirmed tumor response of irinotecan in combination with temozolomide in children with recurrent or refractory medulloblastoma and in children with newly diagnosed high-grade glioma.
Timeline
- Start
- 2007-04
- Primary completion
- 2011-01
- Completion
- 2011-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Irinotecan | Small molecule | 10 mg/m2 | — |
| Subject | Temozolomide | Small molecule | 100 mg/m2 | — |
| Subject | Temozolomide | Small molecule | 125 mg/m2 | — |