drugset / Trial / NCT00405119

A Study To Investigate The Effectiveness Of AH234844 (Lavoltidine) Compared With NEXIUM And Ranitidine.

NCT00405119

Phase 2 Completed 92 enrolled GlaxoSmithKline
RandomizedCrossoverDouble-blindDiagnostic

Summary

Current treatment for gastroesophageal reflux disease (GERD) confirms an unmet need in patients, based on slow onset of action and an inability to provide 24-hour gastric-acid suppression. Clinical data on AH234844 demonstrates a rapid onset of action, high potency, and prolonged duration of effect. The present study endeavors, in part, to compare lavoltidine to two GERD drugs, NEXIUM and ranitidine.

Timeline

Start
2006-05
Primary completion
2007-03
Completion
2007-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Esomeprazole Small molecule 40 mg
Subject Lavoltidine Small molecule
Subject Ranitidine Unknown 300 mg