Adjunctive Glycine for Obsessive Compulsive Disorder

Completed 24 enrolled Nathan Kline Institute for Psychiatric Research Obsessive Compulsive Foundation · collab

RandomizedParallel-groupTriple-blindTreatment

Summary

The purpose of this study is to determine whether individuals with obsessive compulsive disorder who will take a preparation of the amino acid glycine in addition to their current treatment, may experience improvement in their symptoms.

Timeline

Start: 2004-06
Primary completion: —
Completion: 2006-12

Outcome

Missed primary endpoint

paper not quite reaching statistical significance (p=0.053). PMID 19046587 ↗

Publications

Greenberg WM, Benedict MM, Doerfer J, Perrin M, Panek L, Cleveland WL, Javitt DC. Adjunctive glycine in the treatment of obsessive-compulsive disorder in adults. J Psychiatr Res. 2009 Mar;43(6):664-70. doi: 10.1016/j.jpsychires.2008.10.007. Epub 2008 Nov 30.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Glycine	Other / unclassified	60 g	Oral