drugset / Trial / NCT00405639

Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function

NCT00405639

RandomizedParallel-groupTriple-blindBasic science

Summary

The following are done for screening procedures to determine if patients are eligible for this study: blood count, kidney and liver blood tests. Patients will complete a 6-minute walk test. Patients will be instructed to follow a no-added-salt diet for 1-3 weeks before the study and for the whole duration of the study. Diet instructions will be given to the patient and the patient will collect his/her urine for 24 hours before the active study day. Patients will need to avoid strenuous exercise and abstain from smoking, alcohol, and caffeine for 3 days prior to the study days. Patients will remain on their regular medications.

Timeline

Start
2006-06
Primary completion
2011-04
Completion
2013-05

Drugs

EvaluationDrugModalityDoseRoute
Comparator Nesiritide Protein / enzyme biologic 10 ug/kg Subcutaneous