The Effect of Magnesium Sulphate on the Time Course of Rocuronium Induced Neuromuscular Block

Phase 4 Completed 80 enrolled University Hospital, Geneva

RandomizedSingle-groupQuadruple-blindTreatment

Summary

The aim of this study is to investigate whether an optimized pre-treatment with intravenous magnesium enhances the speed of onset of a standard intubation dose of rocuronium.

Timeline

Start: 2006-05
Primary completion: 2008-08
Completion: 2008-08

Publications

Results Czarnetzki C, Lysakowski C, Elia N, Tramer MR. Time course of rocuronium-induced neuromuscular block after pre-treatment with magnesium sulphate: a randomised study. Acta Anaesthesiol Scand. 2010 Mar;54(3):299-306. doi: 10.1111/j.1399-6576.2009.02160.x. Epub 2009 Nov 16.

Drugs

Evaluation	Drug	Modality	Dose	Route
Comparator	Magnesium Sulfate	Other / unclassified	60 mg/kg	Intravenous

Indications

No indication recorded.