Study for the Treatment of Intermittent Allergic Rhinitis With Desloratadine (Study P04683)

Phase 3 Completed 547 enrolled Organon and Co

RandomizedParallel-groupQuadruple-blindTreatment

Summary

This study will investigate the effectiveness of desloratadine in treating subjects with allergic rhinitis (AR) who meet the criteria for intermittent allergic rhinitis.

Timeline

Start: 2006-08
Primary completion: 2007-11
Completion: 2007-11

Outcome

Met primary endpoint

paper The mean reduction of AM/PM reflective T5SS was significantly greater with DL than with placebo over 15 days (-3.01 vs-2.13, P < 0.001) PMID 19624554 ↗

Publications

Results Bousquet J, Bachert C, Canonica GW, Mullol J, Van Cauwenberge P, Bindslev Jensen C, Fokkens WJ, Ring J, Keith P, Lorber R, Zuberbier T; ACCEPT-1 study group. Efficacy of desloratadine in intermittent allergic rhinitis: a GA(2)LEN study. Allergy. 2009 Oct;64(10):1516-1523. doi: 10.1111/j.1398-9995.2009.02115.x. Epub 2009 Jul 14.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Desloratadine	Small molecule	5 mg	—