drugset / Trial / NCT00408590
Recombinant Measles Virus Vaccine Therapy and Oncolytic Virus Therapy in Treating Patients With Progressive, Recurrent, or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer
NaSingle-groupOpen-labelTreatment
Summary
RATIONALE: A gene-modified virus may be able to kill tumor cells without damaging normal cells. PURPOSE: This phase I trial is studying the side effects and best dose of an attenuated oncolytic measles virus therapy and oncolytic virus therapy in treating patients with progressive, recurrent, or refractory ovarian epithelial cancer or primary peritoneal cancer (measles virus vaccine therapy study closed as of 06/02/2008).
Timeline
- Start
- 2004-04-19
- Primary completion
- 2012-08
- Completion
- 2017-11-07
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Carcinoembryonic Antigen-Expressing Measles Virus | Unknown | — | Other |
| Subject | MV-NIS | Unknown | — | Other |