drugset / Trial / NCT00408590

Recombinant Measles Virus Vaccine Therapy and Oncolytic Virus Therapy in Treating Patients With Progressive, Recurrent, or Refractory Ovarian Epithelial Cancer or Primary Peritoneal Cancer

NCT00408590

NaSingle-groupOpen-labelTreatment

Summary

RATIONALE: A gene-modified virus may be able to kill tumor cells without damaging normal cells. PURPOSE: This phase I trial is studying the side effects and best dose of an attenuated oncolytic measles virus therapy and oncolytic virus therapy in treating patients with progressive, recurrent, or refractory ovarian epithelial cancer or primary peritoneal cancer (measles virus vaccine therapy study closed as of 06/02/2008).

Timeline

Start
2004-04-19
Primary completion
2012-08
Completion
2017-11-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Carcinoembryonic Antigen-Expressing Measles Virus Unknown Other
Subject MV-NIS Unknown Other