drugset / Trial / NCT00410358

A Dose Escalation of Gimatecan Administered Orally to Japanese Patients With Advanced Solid Tumor.

NCT00410358

Phase 1 Completed 19 enrolled Novartis Pharmaceuticals
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This study assesses the tolerability, safety, efficacy and pharmacokinetics of gimatecan in Japanese patients. Gimatecan is administered orally for five consecutive days, every 28 days, to adult patients with advanced solid tumors who have progressed despite standard therapy or for whom standard systemic therapy does not exist.

Timeline

Start
2006-06
Primary completion
2008-02
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Gimatecan Small molecule Oral

Indications