drugset / Trial / NCT00413686

Study to Assess Safety of AZD7762 Administered Alone and in Combination With Gemcitabine in Patients With Advanced Solid Malignancies

NCT00413686

Phase 1 Completed 42 enrolled AstraZeneca
Non-randomizedParallel-groupOpen-labelTreatment

Summary

This is an open-label, multi-center, dose-escalation, Phase I study to evaluate the safety, tolerability, and pharmacokinetics and to investigate biomarker changes of AZD7762 administered as a single intravenous unit and in combination with gemcitabine. The study is sponsored by AstraZeneca.

Timeline

Start
2006-12
Primary completion
2010-05
Completion
2010-05

Drugs

EvaluationDrugModalityDoseRoute
Subject AZD7762 Small molecule Intravenous
Subject Gemcitabine Small molecule Intravenous

Indications