A Trial of Placebo Versus Enzastaurin for Lung Cancer Prevention in Former Smokers

Summary

To compare the difference of a marker of cellular proliferation in all bronchial biopsy specimens of former smokers stratified by lung cancer risk, collected before and after treatment per patient between the enzastaurin and placebo groups.

Timeline

Start

2007-12

Primary completion

2010-09

Completion

2010-09

Outcome

Missed primary endpoint

registry analysis (unspecified test); Enzastaurin vs Placebo; p = 0.556; Mean Difference (Final Values) -2.40 (95% CI -10.64 to 5.83) NCT00414960 ↗

Drugs

Indications