drugset / Trial / NCT00415766
Comparison Between Recombinant Versus Urinary hCG for Ovulation Induction in High Responders
RandomizedParallel-groupOpen-labelTreatment
Summary
The purpose of this study is to compare the clinical outcomes of recombinant human chorionic gonadotrophin (rHCG) and urinary HCG (uHCG) in patients undergoing IVF cycles.
Timeline
- Start
- 2013-06
- Primary completion
- 2015-12
- Completion
- 2016-07
Publications
- Background Revelli A, Poso F, Gennarelli G, Moffa F, Grassi G, Massobrio M. Recombinant versus highly-purified, urinary follicle-stimulating hormone (r-FSH vs. HP-uFSH) in ovulation induction: a prospective, randomized study with cost-minimization analysis. Reprod Biol Endocrinol. 2006 Jul 18;4:38. doi: 10.1186/1477-7827-4-38.
- Background Al-Inany HG, Aboulghar M, Mansour R, Proctor M. Recombinant versus urinary human chorionic gonadotrophin for ovulation induction in assisted conception. Cochrane Database Syst Rev. 2005 Apr 18;(2):CD003719. doi: 10.1002/14651858.CD003719.pub2.
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Comparator | rHCG | Protein / enzyme biologic | 250 ug | Subcutaneous |
| Comparator | uHCG | Protein / enzyme biologic | 5000 iu | — |
| Comparator | uHCG | Protein / enzyme biologic | 7500 iu | — |