Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections

Phase 2 Completed 10 enrolled The Center for Rheumatic Disease, Allergy, & Immunology Grifols Therapeutics LLC · collab

Non-randomizedSingle-groupOpen-labelTreatment

Summary

* This is the first study, that we are aware of, that will evaluate the efficacy of IgIV in patients with IgG subclass deficiency. * Will provide data for further collaboration in extending study to involve other immunological centers in the United States to study patients with similar disease.

Timeline

Start: 2004-12
Primary completion: —
Completion: 2006-12

Publications

Abdou NI, Greenwell CA, Mehta R, Narra M, Hester JD, Halsey JF. Efficacy of intravenous gammaglobulin for immunoglobulin G subclass and/or antibody deficiency in adults. Int Arch Allergy Immunol. 2009;149(3):267-74. doi: 10.1159/000199723. Epub 2009 Feb 12.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Immune Globulin Intravenous (Human)	Protein / enzyme biologic	400 mg/kg	Intravenous

Efficacy of IgIv in Patients With IgG Subclass Deficiency and Recurrent Infections

Summary

Timeline

Publications

Drugs

Indications