drugset

drugset / Trial / NCT00418366

A Study on the Effect of Kidney Disease on a Diabetes Medication (0431-008)

NCT00418366 ↗

Phase 1 Completed 24 enrolled Merck Sharp & Dohme LLC

Non-randomizedParallel-groupOpen-labelTreatment

Summary

A study to evaluate the effect of kidney disease, from mild to severe disease, on a diabetes medication

Timeline

Start: 2003-01
Primary completion: 2003-03
Completion: 2003-03

Publications

Results Bergman AJ, Cote J, Yi B, Marbury T, Swan SK, Smith W, Gottesdiener K, Wagner J, Herman GA. Effect of renal insufficiency on the pharmacokinetics of sitagliptin, a dipeptidyl peptidase-4 inhibitor. Diabetes Care. 2007 Jul;30(7):1862-4. doi: 10.2337/dc06-2545. Epub 2007 Apr 27. No abstract available.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Sitagliptin	Small molecule	—	—

Indications