drugset / Trial / NCT00418691

Effects of Methylphenidate Versus Sustained Release Methylphenidate on Cognitive Functioning

NCT00418691

Phase 3 Terminated 34 enrolled M.D. Anderson Cancer Center
RandomizedParallel-groupOpen-labelTreatment

Summary

Primary Objective: * To assess the efficacy of immediate release methylphenidate, sustained release methylphenidate, and the novel vigilance enhancing drug modafinil for the improvement of cognitive functioning in patients with brain tumors.

Timeline

Start
2004-02
Primary completion
2009-11
Completion
2009-11

Drugs

EvaluationDrugModalityDoseRoute
Comparator Methylphenidate Small molecule 10 mg Oral
Comparator Methylphenidate Small molecule 18 mg Oral
Comparator Methylphenidate Small molecule 200 mg Oral
Comparator Modafinil Small molecule 200 mg Oral

Indications