drugset / Trial / NCT00422825
Effect of Food on Bioavailability of a Modified Release Formulation of Imatinib
RandomizedCrossoverOpen-labelTreatment
Summary
This is a single center, four-treatment, four period, crossover study to evaluate the effect of food on the relative bioavailability of a single dose of imatinib (STI571) given as a 800 mg modified release tablet, MR2 compared to twice-daily doses of 400 mg film-coated imatinib tablets. There will be a 10 day wash out phase between treatments and a 1 week safety period at the end of the study. Each participant will receive all four treatments
Timeline
- Start
- 2006-06
- Primary completion
- 2006-09
- Completion
- 2006-09
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Imatinib | Small molecule | 400 mg | — |
| Subject | Imatinib | Small molecule | 800 mg | — |
Indications
No indication recorded.