drugset / Trial / NCT00422903

Letrozole In Combination With Lapatinib In Neoadjuvant Treatment Of Early Breast Cancer

NCT00422903 ↗

Phase 2 Completed 92 enrolled GlaxoSmithKline
RandomizedParallel-groupQuadruple-blindTreatment

Summary

Evaluate the percentage of clinical objective responses (cOR) in patients with HER2 negative early breast cancer treated with pre operative (neoadjuvant)lapatinib and letrozole

Timeline

Start
2007-04
Primary completion
2011-04
Completion
2011-04

Drugs

EvaluationDrugModalityDoseRoute
Subject Lapatinib Small molecule 1500 mg Oral
Subject Letrozole Other / unclassified 2.5 mg Oral

Indications