drugset / Trial / NCT00423878

Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder

NCT00423878

Phase 4 Completed 215 enrolled National Institute of Mental Health (NIMH)
RandomizedParallel-groupSingle-blindTreatment

Summary

The study will compare the effectiveness of antipsychotic medications for patients with schizophrenia or schizoaffective disorder for whom a medication change may be indicated because of an increased risk of cardiovascular disease.

Timeline

Start
2007-01
Primary completion
2009-10
Completion
2010-03

Drugs

EvaluationDrugModalityDoseRoute
Subject Aripiprazole Other / unclassified 5 mg
Subject Aripiprazole Other / unclassified 30 mg
Comparator Olanzapine Small molecule 5 mg
Comparator Olanzapine Small molecule 20 mg
Comparator Quetiapine Small molecule 200 mg
Comparator Quetiapine Small molecule 1200 mg
Comparator Risperidone Other / unclassified 1 mg
Comparator Risperidone Other / unclassified 16 mg