drugset / Trial / NCT00424021
Phase 2 Extension Study of Ambrisentan in Pulmonary Arterial Hypertension
Non-randomizedSingle-groupOpen-labelTreatment
Summary
AMB-220-E is an international, multicenter, open-label study examining the long-term safety of ambrisentan (BSF 208075) in subjects who have previously completed Myogen study NCT00046319, "A Phase II, Randomized, Double-Blind, Dose-Controlled, Dose-Ranging, Multicenter Study of BSF 208075 Evaluating Exercise Capacity in Subjects with Moderate to Severe Pulmonary Arterial Hypertension".
Timeline
- Start
- 2003-04
- Primary completion
- 2009-12
- Completion
- 2009-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Ambrisentan | Small molecule | 1 mg | Oral |
| Subject | Ambrisentan | Small molecule | 2.5 mg | Oral |
| Subject | Ambrisentan | Small molecule | 5 mg | Oral |
| Subject | Ambrisentan | Small molecule | 10 mg | Oral |