drugset / Trial / NCT00424021

Phase 2 Extension Study of Ambrisentan in Pulmonary Arterial Hypertension

NCT00424021

Phase 2 Completed 54 enrolled Gilead Sciences
Non-randomizedSingle-groupOpen-labelTreatment

Summary

AMB-220-E is an international, multicenter, open-label study examining the long-term safety of ambrisentan (BSF 208075) in subjects who have previously completed Myogen study NCT00046319, "A Phase II, Randomized, Double-Blind, Dose-Controlled, Dose-Ranging, Multicenter Study of BSF 208075 Evaluating Exercise Capacity in Subjects with Moderate to Severe Pulmonary Arterial Hypertension".

Timeline

Start
2003-04
Primary completion
2009-12
Completion
2009-12

Drugs

EvaluationDrugModalityDoseRoute
Subject Ambrisentan Small molecule 1 mg Oral
Subject Ambrisentan Small molecule 2.5 mg Oral
Subject Ambrisentan Small molecule 5 mg Oral
Subject Ambrisentan Small molecule 10 mg Oral