drugset / Trial / NCT00425373
Efficacy and Safety of Valsartan and Amlodipine in Patients With Essential Hypertension
RandomizedFactorialTriple-blindTreatment
Summary
The purpose of this study is to evaluate the safety and efficacy of fixed combination of valsartan (40 mg and 80 mg) and amlodipine (2.5 mg and 5 mg), valsartan and amlodipine alone, and placebo in reducing blood pressure. The study will investigate the dose response relationship for the combinations, monotherapies, and placebo.
Timeline
- Start
- 2006-11
- Primary completion
- 2008-03
- Completion
- 2008-03
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Amlodipine | Other / unclassified | 2.5 mg | — |
| Subject | Amlodipine | Other / unclassified | 5 mg | — |
| Subject | Valsartan | Small molecule | 40 mg | — |
| Subject | Valsartan | Small molecule | 80 mg | — |