drugset / Trial / NCT00425854

An Open Label Phase II Trial of BIBW 2992 in Patients With HER2-negative Metastatic Breast Cancer

NCT00425854

Phase 2 Completed 50 enrolled Boehringer Ingelheim
Non-randomizedParallel-groupOpen-labelDiagnostic

Summary

The purpose of this trial is to evaluate the efficacy, safety and pharmacokinetics of BIBW 2992, a dual, irreversible EGFR- and HER2-inhibitor, in two cohorts of patients with HER2-negative breast cancer after failure of no more than three regimen of prior chemotherapy.

Timeline

Start
2006-11
Primary completion
2009-05
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Afatinib Small molecule 50 mg Oral

Indications