A Study of Recombinant Vaccinia Virus to Treat Malignant Melanoma

Summary

The purpose of this research study is to find out whether JX-594 (Pexa-Vec) is safe and effective for treating surgically unresectable malignant melanoma.

Timeline

Start

2007-03

Primary completion

2008-02

Completion

2009-12

Publications

• Background Mastrangelo MJ, Maguire HC Jr, Eisenlohr LC, Laughlin CE, Monken CE, McCue PA, Kovatich AJ, Lattime EC. Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma. Cancer Gene Ther. 1999 Sep-Oct;6(5):409-22. doi: 10.1038/sj.cgt.7700066.

Drugs

Indications