Tumor Necrosis Factors (TNF)-α Blockade for Psoriatic Arthritis

Summary

The purpose of this study is: * To elucidate the immunomodulating properties of anti-TNF-α therapy in patients with psoriatic arthritis (PsA). * To ascertain whether magnetic resonance imaging (MRI) is a sensitive tool in measuring early response after therapy with anti-TNF-α in the PsA wrist using the Outcome Measures in Rheumatoid Arthritis Clinical Trials (OMERACT) guidelines for rheumatoid arthritis (RA). * To assess whether the lipid and other cardiovascular risk profiles would improve after anti-TNF-α therapy in patients with PsA.

Timeline

Start

2006-05

Primary completion

2009-03

Completion

2009-03

Drugs

Indications