A Study to Compare Multiple Doses Intravitreal Microplasmin for Treatment of Patients With Vitreomacular Traction (MIVI-IIt)

Summary

A multicenter study to compare multiple doses of intravitreal microplasmin for non-surgical PVD induction for treatment of patients with vitreomacular traction.

Timeline

Start

2007-02

Primary completion

2009-01

Completion

2009-02

Outcome

Missed primary endpoint

registry analysis (superiority or other test); Ocriplasmin 75µg Single Injection vs Sham Injection; p = 0.4762; Fisher Exact NCT00435539 ↗

registry analysis (superiority or other test); Ocriplasmin 175µg Single Injection vs Sham Injection; p = 0.4762; Fisher Exact NCT00435539 ↗

registry analysis (superiority or other test); Ocriplasmin 125µg Pooled vs Sham Injection; p = 0.5343; Fisher Exact NCT00435539 ↗

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Ocriplasmin	Protein / enzyme biologic	75 ug	Intravitreal
Subject	Ocriplasmin	Protein / enzyme biologic	125 ug	Intravitreal

Indications