A Study of Multiple Dosing Regimens of IV Conivaptan in Subjects With Euvolemic or Hypervolemic Hyponatremia

Phase 4 Completed 121 enrolled Cumberland Pharmaceuticals

RandomizedParallel-groupDouble-blindTreatment

Summary

The study will evaluate the effectiveness and safety of multiple dosing regimens of IV conivaptan in subjects with euvolemic or hypervolemic hyponatremia

Timeline

Start: 2007-01
Primary completion: 2008-09
Completion: 2008-09

Publications

Background Kalra S, Efrati S, Arthur JM, Oliven A, Velez JC, McNutt BE, Klasen S, Abeyratne A. Effect of loading dose and formulation on safety and efficacy of conivaptan in treatment of euvolemic and hypervolemic hyponatremia. Am J Health Syst Pharm. 2011 Apr 1;68(7):590-8. doi: 10.2146/ajhp100243.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Conivaptan	Small molecule	20 mg	Intravenous

Indications

No indication recorded.