drugset
drugset / Trial / NCT00437177

Relationship Between D2 Receptors SPECT and the Apomorphine Test in Patients With OH Dependence (ALC-DRD2-APO)

NCT00437177 ↗

Phase 2 Unknown 50 enrolled Hospital Universitari Vall d'Hebron Research Institute
Non-randomizedSingle-groupOpen-labelBasic science

Summary

OH dependence is associated with DA receptor changes. Both, the apomorphine test and the D2Rec SPECt are usefull for monitoring DA receptor status. We aimed at studying whether DA receptor hypofunction, assessed by means of the apomorphine test and the D2Rec SPECT, is a marker of relapse in detoxified OH dependents patients.

Timeline

Start
2007-01
Primary completion
2009-12
Completion
2010-06

Drugs

EvaluationDrugModalityDoseRoute
Subject Apomorphine Unknown 0.05 mg/kg Subcutaneous
Subject [(123)I] iodobenzamide Unknown 185 mbq Intravenous

Indications

alcohol dependence