drugset / Trial / NCT00439166
Effects of Doxycycline and Rifampicin on Biomarkers of Alzheimer's Disease in the Cerebrospinal Fluid
Phase 3
Completed
100 enrolled
Hamilton Health Sciences Corporation
The Physicians' Services Incorporated Foundation · collab
Non-randomizedFactorialQuadruple-blindTreatment
Summary
This study will determine if biomarkers found in the cerebrospinal fluid of people with Alzheimer's disease, are affected by treatment with two common antibiotics, doxycycline and rifampicin, suggesting a disease-modifying effect of those treatments.
Timeline
- Start
- 2007-02
- Primary completion
- 2010-04
- Completion
- 2010-12
Drugs
| Evaluation | Drug | Modality | Dose | Route |
|---|---|---|---|---|
| Subject | Doxycycline | Small molecule | 100 mg | — |
| Subject | Rifampin | Small molecule | 300 mg | — |