Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%

Phase 4 Completed 40 enrolled Allergan

RandomizedParallel-groupSingle-blindTreatment

Summary

Patients with glaucoma or ocular hypertension currently being treated with latanoprost 0.005%, and in need of additional IOP lowering will be randomized to receive either brimonidine 0.1% or brinzolamide 1% three-times daily as adjunctive therapy to latanoprost 0.005%

Timeline

Start: 2006-07
Primary completion: 2007-03
Completion: 2007-03

Publications

Day DG, Hollander DA. Brimonidine purite 0.1% versus brinzolamide 1% as adjunctive therapy to latanoprost in patients with glaucoma or ocular hypertension. Curr Med Res Opin. 2008 May;24(5):1435-42. doi: 10.1185/030079908x301848. Epub 2008 Apr 9.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Brimonidine	Small molecule	0.1 %	Other
Comparator	Brinzolamide	Small molecule	1 %	Other
Background	Latanoprost	Small molecule	0.005 %	Other

Brimonidine 0.1% Versus Brinzolamide 1% as Adjunctive Therapy to Latanoprost 0.005%

Summary

Timeline

Publications

Drugs

Indications