drugset / Trial / NCT00440388

Safety & Efficacy Study of AT-101 in Combination w/ Rituximab in Previously Untreated Grade I-II Follicular Non-Hodgkin's Lymphoma

NCT00440388

Phase 2 Completed 23 enrolled Ascenta Therapeutics
Non-randomizedSingle-groupOpen-labelTreatment

Summary

This is a phase II clinical trial in patients who have not received systemic treatment for follicular non-Hodgkin's lymphoma. The study combines rituximab, an approved drug for this disease, with AT-101, an experimental drug. The hypothesis is that by adding AT-101 to the rituximab regimen, improvement to patients' response to the treatment will be observed verses rituximab alone.

Timeline

Start
2006-10
Primary completion
2008-11
Completion
2008-11

Drugs

EvaluationDrugModalityDoseRoute
Subject AT-101 Small molecule 30 mg Oral
Subject Rituximab Monoclonal antibody 375 mg/m2 Intravenous

Indications