drugset

drugset / Trial / NCT00441961

Treatment With High Dose Methotrexate in Patients With Eosinophilic Fasciitis

NCT00441961 ↗

Completed 6 enrolled Radboud University Medical Center

Non-randomizedSingle-groupOpen-labelTreatment

Summary

Evaluate the effect of high dose MTX on skin induration in patients with eosinophilic fascia.

Timeline

Start: 2006-10
Primary completion: 2010-12
Completion: 2011-06

Publications

Mertens JS, Zweers MC, Kievit W, Knaapen HK, Gerritsen M, Radstake TR, van den Hoogen FH, Creemers MC, de Jong EM. High-Dose Intravenous Pulse Methotrexate in Patients With Eosinophilic Fasciitis. JAMA Dermatol. 2016 Nov 1;152(11):1262-1265. doi: 10.1001/jamadermatol.2016.2873.

Drugs

Evaluation	Drug	Modality	Dose	Route
Subject	Methotrexate	Small molecule	4 mg/kg	Intravenous

Indications