drugset / Trial / NCT00444158

Double-Blind, Double-Dummy, 2-Period Crossover of a 20-Minute Versus a 4-hour IV of MOA-728 in Stable Methadone Subjects

NCT00444158

Phase 1 Completed 24 enrolled Bausch Health Americas, Inc.
RandomizedCrossoverDouble-blindTreatment

Summary

MOA-728, an investigational drug, is currently being studied for the relief of constipation associated with postoperative ileus and treatment of opioid induced constipation in patients receiving palliative care. This study will further investigate the IV formulation of MOA-728 comparing PK/PD time points for a 20-minute versus a 4-hour infusion.

Timeline

Start
2007-03
Primary completion
Completion
2007-07

Drugs

EvaluationDrugModalityDoseRoute
Subject Methylnaltrexone Other / unclassified Intravenous

Indications