drugset / Trial / NCT00446589

The Effects of Ibandronate or Teriparatide Therapy on Bone Histology and Biochemical Indices in Patients on Hemodialysis With Low Bone Mineral Density

NCT00446589

Phase 4 Terminated 19 enrolled Papageorgiou General Hospital
Non-randomizedSingle-groupOpen-labelTreatment

Summary

Hemodialysis patients with low bone density (total hip T-score \<-2.5) will be assigned to receive teriparatide (those with histologic confirmation of adynamic bone disease) or ibandronate (subjects with increased osteoclast number on bone biopsy). Follow-up period: one year. A second bone biopsy at the end of the study.

Timeline

Start
2006-07
Primary completion
Completion

Drugs

EvaluationDrugModalityDoseRoute
Subject Ibandronate Other / unclassified 1 mg Intravenous
Subject Teriparatide Protein / enzyme biologic Subcutaneous

Indications